Best Eye Drop Grade Sodium Hyaluronate for Ophthalmic Preparations Manufacturer, Factories

Eye drop grade sodium hyaluronate refers to high-purity sodium hyaluronate that meets the quality standards for ophthalmic preparations. It is typically produced through microbial fermentation and is not derived from animals. This grade of product has strict requirements regarding molecular weight distribution, purity, aseptic control, endotoxin content, and biocompatibility, making it suitable for formulation systems that come into direct contact with the ocular surface.

Product Description

Product Specification

Product Name Sodium Hyaluronate
Chemical Formula (C14H20NNaO11)n
Chemical Structure
Chemical Structure of Sodium Hyaluronate
CAS No. 9067-32-7
Appearance White, fine powder
Assay ≥99.5%
Application Ophthalmic care
Function Moisturizes and lubricates the ocular surface, relieving dry eye discomfort.
Solubility Soluble in water
Heavy metals ≤10ppm
Protein ≤0.1%
Bacterial endotoxins ≤0.5IU/mg
Source Microbial fermentation
Packaging 100g/foil bag, 1kg/foil bag or as per customer’s request.
Shelf life 2 years
Storage conditions Avoid light, refrigerate 2℃~10℃, seal container.

Application Fields

1. Artificial Tears & Lubricating Eye Drops
Eye drop-grade sodium hyaluronate possesses excellent water-retention and viscoelastic properties, forming a stable hydration protective layer on the ocular surface to help maintain tear film stability. It is commonly used in artificial tears and lubricating eye drops to relieve dry eye and discomfort.
2. Ocular Surface Protection & Repair
Sodium hyaluronate exhibits good biocompatibility with ocular surface tissues, providing lubrication and protection, reducing blinking friction, and aiding in the stabilization of the ocular surface environment and the repair of minor damage. It is suitable for ocular surface care and postoperative care formulations.
3. Drug Delivery Optimization
Due to its excellent adhesion and rheological properties, eye drop-grade sodium hyaluronate helps prolong the residence time of formulations on the ocular surface, enhancing the persistence of action of active ingredients and improving the comfort of eye drops.
4. Preservative-Free Ophthalmic Systems
Eye drop grade sodium hyaluronate is suitable for preservative-free or low-irritant ophthalmic formulations and can be used in single-dose or multi-dose formulations to meet the safety requirements of long-term or high-frequency use and people with sensitive eyes.

Frequently Asked Questions

Q: What is the source of your Sodium Hyaluronate?
Our Sodium Hyaluronate is produced through microbial fermentation, which ensures high purity, excellent biocompatibility, and consistent quality suitable for ophthalmic applications.
Q: What is the assay purity and quality standard of this product?
The product features an assay purity of ≥99.5%, with extremely low protein content (≤0.1%) and low bacterial endotoxins (≤0.5IU/mg) to meet rigorous ophthalmic care standards.
Q: How should this product be stored to maintain its shelf life?
To guarantee a 2-year shelf life, it must be stored in a sealed container, protected from light, and kept refrigerated at temperatures between 2℃ and 10℃.
Q: Can this grade of Sodium Hyaluronate be used in preservative-free formulations?
Yes, it is highly suitable for preservative-free or low-irritant ophthalmic systems, making it ideal for single-dose or multi-dose eye drop formulations targeted at sensitive eyes.
Q: What packaging options are available?
Standard packaging options include 100g/foil bag and 1kg/foil bag. Customized packaging solutions are also available based on customer requirements.

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